Nipah, Gates and Singapore - Pirbright Institute - No Time to Die - And the People Become the Weapon

As of January 2026, there are no officially approved vaccines for the Nipah virus (NiV), but several candidates are in development, with significant funding and collaboration involving the Bill & Melinda Gates Foundation, the Coalition for Epidemic Preparedness Innovations (CEPI), and research entities based in Singapore.

Key Developments in Nipah Vaccines and Funding

CEPI Funding: CEPI, an organization supported by the Gates Foundation, has awarded millions in funding for Nipah vaccine candidates, including a 2019 contract for up to US$31 million to the University of Tokyo to develop a vaccine using a measles vector.

Vaccine Candidates: Research focuses on viral vector vaccines (similar to Ebola vaccines) and subunit vaccines. A promising rVSV-Nipah candidate has received up to $43.6 million in funding from CEPI for development.

Phase 1 Trials: A candidate subunit vaccine showed promising safety and immunogenicity in a Phase 1 trial, with results published in November 2025.

Singapore's Role and Collaboration

Research and Conferences: Singapore is actively involved in regional preparedness and research, hosting a major conference on Nipah virus, bringing together global stakeholders including Duke-NUS, CEPI, and the National Institutes of Health (NIH).

Gates Foundation Presence: The Bill & Melinda Gates Foundation is establishing an office in Singapore to strengthen partnerships for global health in Asia, with a focus on vaccine development.

Surveillance: Singapore has tightened airport screenings in response to recent Nipah outbreaks in India, although no cases have been detected in Singapore in the current 2026 outbreak wave.

Current Status

No Cure/Vaccine: Currently, only supportive care is available for infected patients, with case fatality rates ranging from 40% to 75%.

Urgent Need: The WHO has classified Nipah as a priority disease with pandemic potential, making the development of these vaccines highly urgent.

The collaborations between Singapore and partners like the Gates Foundation are aimed at accelerating the development of these vaccines to prevent future outbreaks.

Gates and Singapore

Bill Gates visited Singapore in early May 2025 for a two-day trip, highlighting the Bill & Melinda Gates Foundation's plans to establish a new regional office in the city-state. During his visit, he met with government leaders, including Prime Minister Lawrence Wong, and explored local culture by trying hawker food like chicken rice and durian at the Newton Food Centre.

Key Details of the Visit:

Purpose: To establish a new Asia regional office for the Gates Foundation, focusing on health, technology, and philanthropy.

Key Meetings: Met with senior government leaders, including Prime Minister Lawrence Wong and senior officials.

Activities: Spoke at the Philanthropy Asia Summit 2025 and met with Breakthrough Energy partners.

Local Experience: Visited Newton Food Centre to sample local dishes, including satay, chicken rice, and durian.

Observations: Described Singapore as "talented," "forward-looking," and a key location for regional health solutions.

This visit marked a significant step in expanding the foundation's footprint in Asia, leveraging Singapore's technological and philanthropic ecosystem.

Gates Foundation

Based on recent reports, the Singaporean government has supported the establishment of a Bill & Melinda Gates Foundation office in Singapore to foster collaboration on health and development, but it has not directly given money to the foundation.

Rather than a transfer of funds to the foundation, the relationship focuses on partnership and investment in regional initiatives:

Office Setup Support: The Singapore Economic Development Board (EDB) is supporting the establishment of the Gates Foundation's 12th global office in Singapore, which was announced in May 2025 to boost partnerships across Southeast Asia.

Collaborative Initiatives: Instead of funding the foundation, Singaporean entities, such as the Temasek Trust, are collaborating with the Gates Foundation on regional health and sustainability initiatives.

Philanthropy Hub Strategy: The move aligns with Singapore's aim to become a regional philanthropic hub, with the government providing incentives for philanthropy while the Gates Foundation seeks to leverage Singapore's expertise in AI, fintech, and healthcare.

Bill Gates noted that the foundation aims to work with local entities (like Temasek Trust and local universities) to improve regional health, rather than receiving funding from them.

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Gates Foundation Trust https://share.google/BYxdkeQOXYoKErpLT

Financials

Gates Foundation Trust

Gates Foundation Trust

The Gates Foundation makes grants and strategic investments aligned with our mission and identified priority focus areas. The money for that activity—the foundation’s endowment—is held and managed by the Gates Foundation Trust. This two-entity structure enables us to keep our program work separate from decisions about investing our assets. This ensures that the foundation’s experts can focus solely on our mission.

How the trust works

Our endowment has been funded by our co-founders, Bill Gates and Melinda French Gates, and Warren Buffett, the former CEO of Berkshire Hathaway. Among the three, Bill and Warren continue to make contributions to the endowment. Bill is the trustee of the Gates Foundation Trust, and the endowment is managed by Cascade Asset Management Company, whose independent investment managers are not directly affiliated with the foundation. Warren has no involvement in the investment of the endowment through the Foundation Trust, including decisions that might be made regarding Berkshire Hathaway Inc. stock.

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WHO Pandemic Agreement - Global https://share.google/HPIvhU34x5DiREtGH

The WHO Pandemic Agreement was adopted by the World Health Assembly on 20 May 2025, marking a historic moment for global public health. The devastating impact of the COVID-19 pandemic revealed significant gaps and inequities in the world's ability to prevent and respond to health emergencies, prompting nations to take action. Launched in 2021, the negotiation process involved three years of intensive work by governments, in consultation with relevant stakeholders and experts. The aim of the Intergovernmental Negotiating Body established for this process was to draft and negotiate a WHO convention, agreement or other international instrument on pandemic prevention, preparedness and response, that would culminate in a legally binding international instrument designed to make the world safer and more equitable in the face of future pandemics.

Following its adoption, the next crucial step is for an Intergovernmental Working Group (IGWG) on the Pandemic Agreement to negotiate the details of the Pathogen Access and Benefit-Sharing (PABS) system, which will form an annex to the Agreement. Once this annex is adopted by the World Health Assembly, the full Agreement will be open for countries to sign and ratify according to their own constitutional processes. The Agreement will officially enter into force 30 days after 60 countries have ratified it.

Definitions

Based on recent developments, including the adoption of a new "Pandemic Agreement" by the World Health Organization (WHO) member states in May 2025, the framework for managing pandemics is evolving to focus on prevention, equity, and reducing the impact on health systems and lives.

Here is a breakdown of the current situation regarding WHO, pandemic definitions, and the goal of reducing mortality:

1. Has the WHO Definition of "Pandemic" Changed?

The Context: Following the COVID-19 pandemic, the WHO has worked on a comprehensive framework (the Pandemic Agreement) to improve international cooperation.

Newer Definition Focus: A key focus in these discussions, often influenced by the lessons from COVID-19, is defining pandemics by their global spread, high transmissibility, and ability to overwhelm health systems, necessitating a rapid, coordinated response.

Preventative Focus: The new agreement, adopted on May 20, 2025, emphasizes preventing future devastation, protecting lives, and ensuring equitable access to countermeasures (vaccines, therapeutics).

2. "Nobody Need Die" - Goal vs. Reality

The goal of updated pandemic planning is to significantly reduce mortality, but it is not a declaration that future pandemics will not cause death.

Focus on Mitigation: The goal is to avoid high mortality by creating a "safer world" with faster, better-coordinated, and more equitable responses compared to the COVID-19 pandemic.

Equitable Access: The 2025 agreement focuses on sharing vaccines and technology, with a goal to have 20% of real-time production of vaccines and diagnostics available for countries in need during a pandemic.

Ongoing Risks: Despite improvements in preparedness, pandemics by definition (large-scale outbreaks) represent a major, sometimes fatal, risk to public health.

3. Key Changes in the 2025 Pandemic Agreement

Member-State Driven: The new agreement was developed by member states to address inequities in past responses.

No Mandatory Lockdown Power: The agreement does not give the WHO the power to impose mask or vaccine mandates or lockdowns.

Pathogen Access: It sets up a new system for sharing, access, and benefit-sharing of pathogens to speed up vaccine development.

Summary: The focus is shifting toward "ending the pandemic threat" through faster, more equitable, and better-resourced responses, rather than merely treating it as a naturally occurring disaster that cannot be managed. However, the risk of mortality remains high in any new, significant infectious disease outbreak.

Gates, Buffett and the Gates Foundation

Warren Buffett is a prominent member of the exclusive "$100 billion club," joining elite individuals like Elon Musk and Jeff Bezos in 2021. His massive fortune,, largely built through Berkshire Hathaway, is characterized by long-term compounding, with the majority earned after age 65, and a commitment to philanthropy. He also launched the Secret Millionaires Club, an animated series teaching financial literacy to children.

Key Details Regarding Warren Buffett's Wealth and "Club" Status:

$100 Billion Club: In March 2021, Buffett became the sixth person to join this rarefied group, with his fortune largely driven by Berkshire Hathaway stock.

Wealth Generation: $81.5 billion of his $84.5 billion fortune was earned after his 65th birthday, highlighting the impact of time and compounding on his wealth.

Philanthropy: Despite his high net worth, he has donated over $37 billion in Berkshire stock since 2006.

The Secret Millionaires Club: Buffett created an educational series (and accompanying book) to teach children and young entrepreneurs about financial responsibility, investing, and business.

Investment Philosophy: Known as a "value investor," his principles emphasize long-term, rational thinking, and understanding what you invest in.

"Secret Billionaires' Club" Concept

Some discussions, such as those by author Robert P. Miles, refer to the select group of investors and business partners who have achieved massive success by studying and implementing Buffett's investment strategies as a "Secret Billionaires' Club".

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The Pirbright Institute

DNA-launched Nipah virus vaccines and therapeutics | Research project | The Pirbright Institute https://share.google/RYV4aYro8HO50gTFp

DNA has advantages over other platforms for delivery of vaccines and therapeutics, such as low production cost, time-to-impact and enhanced stability for transportation/storage. This project exploits our recently established DNA-delivery platform in the context of Nipah virus vaccines and therapeutics. Whilst the protective antigens from the Nipah virus are well defined and could be readily engineered in the DNA vaccine platform, there are a limited number of human monoclonal antibody-based therapeutic candidates, with only one in clinical testing. We therefore aim to isolate new therapeutic candidate monoclonal antibodies from human volunteers in Malaysia, who previously recovered from Nipah virus infection.

What does DNA based mean exactly? We know that they've been collecting our DNA during the Covid scamdemic🙃

No Time To Die

In No Time to Die, the villain Safin uses a nanobot bioweapon called "Heracles" designed to target and kill specific individuals based on their DNA. The virus acts as a programmable, contagious poison, where infection occurs through physical contact, leading to almost instant death. It is used to target Madeleine Swann and her daughter, Mathilde, and is ultimately used on James Bond, making it impossible for him to touch them without killing them. 

Key details about the DNA-targeted bioweapon:

• Targeting Method: The nanobots are programmed to identify and destroy specific DNA markers.

• Heracles Virus: Initially developed by the British government to kill, it was stolen by SPECTRE and modified by Safin to target specific individuals, such as those with Madeleine Swann's DNA.

• Contagious Nature: The weapon is designed to spread, making anyone carrying it a lethal risk to the target.

• Bond's Sacrifice: Because Bond is infected and can never safely be with Madeleine or his daughter, he chooses to stay on the island to be killed by the missile strike, ensuring the weapon cannot be used further.

• Plot Device: The film explores the concept of "DNA insecurity" and the threat of genetically targeted,,,{"type":"text","value":""}novel biological warfare,1,. 

Nanotechnology

Heracles was a DNA-targeting nanotechnology bioweapon developed in collaboration with the British Secret Intelligence Service (SIS/MI6). It was featured prominently in the 2021 James Bond film, No Time to Die.

As for establishing people's DNA........

Yes, nose swabs can be used to collect human DNA for testing purposes, although they are more commonly associated with detecting viral RNA (like COVID-19). Nose swabs can effectively collect human epithelial cells from the mucosal lining, which can then be analyzed for genetic information. 

Here are the key details regarding nose swabs and DNA testing:

• Type of Data: While typical COVID-19 nasal swabs are designed to detect the genetic material of a virus (RNA), these tests also collect human epithelial cells in the process.

• Suitability for Genetic Testing: Studies have shown that nasal swabs are an effective, non-invasive alternative to blood samples for collecting high-quality DNA, particularly for SNP (single nucleotide polymorphism) genotyping.

• Effectiveness: Research indicates that nasal swabs can provide a high DNA yield and good quality results, often with 100% concordance with blood samples.

• Comparison to Buccal Swabs: While cheek (buccal) swabs are more common for direct-to-consumer DNA tests, specialized nasal swabs can also be used.

• Limitations: The amount of DNA collected from a nasal swab can be highly variable depending on the technique used and the amount of mucus, making it sometimes less reliable than other methods for genetic testing. 

Note on COVID-19 Tests: While the technology exists, the specific nasal swabs used for routine COVID-19 testing are generally not used to profile an individual's DNA. (ACCORDING TO AI).

We only have AI's word that the tests were not used for profiling 😃😃😃😃😃😃😃🤣🤣🤣🤣🤣🤣🤣🤣

How to Collect Nasal Discharge for DNA Testing https://share.google/GT1L5VfBUShaZmR4W